| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-1271 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-1270 | Imported from RMgmDB | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-1271
Reduced growth/multiplication of asexual blood stages |
Imported from RMgmDB |
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-1270
Reduced growth/multiplication of asexual blood stages |
Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-1271
Reduced gametocyte production |
Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-1270
Reduced gametocyte production |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1270
Strongly reduced ookinete formation |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1271
Strongly reduced ookinete formation |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1270
Strongly reduced oocyst formation |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1271
Strongly reduced oocyst formation |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1270
No sporozoite formation |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1271
No sporozoite formation |
Imported from RMgmDB |
| P. falciparum 3D7 | Asexual |
Attenuated |
24453970 (Conditional)
\" To investigate its importance in P. falciparum, we generated a pepc null mutant (D10(Δpepc) ), which was only achievable when malate, a reduction product of oxaloacetate, was added to the growth medium. D10(Δpepc) had a severe growth defect in vitro, which was partially reversed by addition of malate or fumarate, suggesting that pepc may be essential in vivo. \" |
Theo Sanderson, Francis Crick Institute |
| PlasmoDB | PBANKA_1017900 |
| GeneDB | PBANKA_1017900 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PB000844.03.0, PBANKA_101790 |
| Orthologs | PCHAS_1018700 , PF3D7_1426700 , PKNH_1332000 , PVP01_1322600 , PVX_085200 , PY17X_1019400 |
| Google Scholar | Search for all mentions of this gene |