Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. berghei ANKA | Asexual |
No difference |
RMgm-220 | Imported from RMgmDB |
P. berghei ANKA | Asexual |
No difference |
RMgm-5215 | Imported from RMgmDB |
P. berghei ANKA | Gametocyte |
No difference |
RMgm-220 | Imported from RMgmDB |
P. berghei ANKA | Gametocyte |
No difference |
RMgm-5215 | Imported from RMgmDB |
P. berghei ANKA | Ookinete |
No difference |
RMgm-220 | Imported from RMgmDB |
P. berghei ANKA | Ookinete |
No difference |
RMgm-5215 | Imported from RMgmDB |
P. berghei ANKA | Oocyst |
No difference |
RMgm-220 | Imported from RMgmDB |
P. berghei ANKA | Oocyst |
No difference |
RMgm-5215 | Imported from RMgmDB |
P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-220
Normal numbers of oocysts are produced. The number of midgut sporozoites per mosquito was comparable to wild type. Only a few sporozoites were found to be associated with the salivary glands. Conversely, the number of hemolymph sporozoites significantly increased, indicating that they were normally released from the oocysts but accumulated in the hemolymph as a result of the lack of sporozoite entry into the salivary gland.Midgut sporozoites showed normal gliding motility. Mutant midgut sporozoites showed an infectivity to rats comparable to wild type midgut sporozoites. |
Imported from RMgmDB |
P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-5215
Midgut ( sporozoites are formed but fail to invade salivary glands. No salivary gland sporozoites. |
Imported from RMgmDB |
P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-220
Mutant midgut sporozoites showed an infectivity to rats comparable to wild type midgut sporozoites as shown by infection rates and prepatent period in rats after intravenous injection of sporozoites. |
Imported from RMgmDB |
P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-5215
Midgut (hemolymph) sporozoites have reduced infectivity to mice (see additional remarks phenotype below) |
Imported from RMgmDB |
PlasmoDB | PBANKA_0901300 |
GeneDB | PBANKA_0901300 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | PB000798.02.0, PBANKA_090130, PBANKA_0901300.1, PBANKA_0901300.2, PbMAEBL |
Orthologs | PCHAS_0702500 , PF3D7_1147800 , PF3D7_1147800 , PKNH_0945700 , PVP01_0948400 , PVX_092975 |
Google Scholar | Search for all mentions of this gene |