Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
21251930 Theo Sanderson, Wellcome Trust Sanger Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Left: Immunofluorescence microscopy of erythrocytes infected with trophozoite stage P. falciparum. Bright fields showing parasite morphology were collected by differential interference contrast. Fluorescence images were taken after reaction with antibody PABHK and FITC-conjugated secondary antibody. Arrows indicate an intense spot of fluorescence frequently observed. PfVP1 is localized to the parasite plasma membraneRight: Epifluorescence of P. falciparum transfected with GFP gene fusions. Trophozoite transfected with PfVP1–GFP gene fusion showing a membrane bound parasite surface distribution and a bright spot of fluorescence.McIntosh MT, Drozdowicz YM, Laroiya K, Rea PA, Vaidya AB. Two classes of plant-like vacuolar-type H(+)-pyrophosphatases in malaria parasites. Mol Biochem Parasitol. 2001 114:183-95. Copyright Elsevier 2009.

See original on MMP

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