Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

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Imaging data (from Malaria Metabolic Pathways)

A P. falciparum-infected erythrocyte expressing PfPiT-HA (green) and nucleus stained with Hoechst 33258 (blue). Within the infected cell, PfPiT-HA localizes to the parasite. Lower row of three panels: PfPiT localizes to the parasite surface, co-localizing with PfENT1 (red), a transport protein shown previously to reside on the plasma membrane of the parasite.Saliba KJ, Martin RE, Bröer A, Henry RI, McCarthy CS, Downie MJ, Allen RJ, Mullin KA, McFadden GI, Bröer S, Kirk K. Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite. Nature. 2006 443:582-5.

See original on MMP

A P. falciparum-infected erythrocyte expressing PfPiT-HA (green) and nucleus stained with Hoechst 33258 (blue). Within the infected cell, PfPiT-HA localizes to the parasite. Lower row of three panels: PfPiT localizes to the parasite surface, co-localizing with PfENT1 (red), a transport protein shown previously to reside on the plasma membrane of the parasite.Saliba KJ, Martin RE, Bröer A, Henry RI, McCarthy CS, Downie MJ, Allen RJ, Mullin KA, McFadden GI, Bröer S, Kirk K. Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite. Nature. 2006 443:582-5

See original on MMP

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