Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-146 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4933 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-146 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4933 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-146 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4933 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-146
Normal numbers of gametocytes, gametes, zygotes and mature ookinetes are formed. In Giemsa stained smears the morphology of mutant ookinetes is comparable to that of wild type ookinetes. Ookinetes have a reduced (30-90%) capacity to produce oocysts in A. stephensi mosquitoes(see phenotype 'Oocysts').
Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4933 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-146
When fed to A. stephensi mosquitoes, significant reductions in oocyst numbers of between 30 and 90% were obtained with the mutant parasites. The oocyst formed, produced normal numbers of sporozoites, that were infectious to the mammalian host.
Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-4933 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-146 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-146 Imported from RMgmDB

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