Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4832 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4832
Reduced growth of asexual blood stages. Pbyop1 parasites have a multiplication rate of approximately 7-fold over 24 h compared to 10-fold for 127 WT parasites.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4832
Reduced oocysts and sporozoite loads. Partially (?) explained by reduced growth of blood stages.
Imported from RMgmDB

More information