Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
https://www.biorxiv.org/content/early/2018/07/18/371484
With CRISPR
Theo Sanderson, Google
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Refractory
https://www.biorxiv.org/content/early/2018/07/18/371484 (Knock down)
delayed phenotype of slow growth. KD parasites are hypersensitive to saponin. Dramatic changes in formation and morphology of digestive vacuoles.
Theo Sanderson, Google

More information