Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5080 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5081 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
Possible
35638735
\"P. falciparum ARID (PfARID) localized to the parasite nucleus and is critical for the formation of male gametes and fertility of female gametes. PfARID gene deletion (Pfarid-) gametocytes showed downregulation of gene expression important for gametogenesis, antigenic variation, and cell signaling and for parasite development in the mosquito.\"
Theo Sanderson, Francis Crick Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-5080 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5081 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5080
Infertile males; females fertile
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5081
Infertile males, fertile females.
Imported from RMgmDB
P. falciparum 3D7 Gametocyte
Attenuated
35638735
\"P. falciparum ARID (PfARID) localized to the parasite nucleus and is critical for the formation of male gametes and fertility of female gametes. PfARID gene deletion (Pfarid-) gametocytes showed downregulation of gene expression important for gametogenesis, antigenic variation, and cell signaling and for parasite development in the mosquito.\"
Theo Sanderson, Francis Crick Institute
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5080
Infertile males; females fertile.Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5081
Infertile males, fertile females.Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5080
Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5081
Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes
Imported from RMgmDB

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