Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
RMgm-1363 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-1038 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Egress defect
https://www.biorxiv.org/content/10.1101/2020.01.05.890483v1 (Conditional)
DD knockdown. Defects in DNA replication when knocked down early in IDC. Defects in nuclear division when knocked down later. IMC fails to form. Complete block in egress even upon knockdown after DNA replication. Recapitulated with DiCre-based knockdown.
Theo Sanderson, Francis Crick Institute

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