Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5220 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
Difference from wild-type
RMgm-5220
(Slightly) reduced growth/multiplication of asexual blood-stage parasites in mice.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5220
(Slightly) reduced formation of female gametocytes
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5220
Reduced ookinete production. Mature ookinetes formed had a similar (light-microscope) morphology as wild-type ookinetes.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5220
Reduced oocyst production. Presence of degenerated, vacuolated oocysts. No sporozoite formation inside oocysts.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5220
No salivary gland sporozoites
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-5220
No infection of mice by mosquito bite.
Imported from RMgmDB

More information