Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-348 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-347 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-348 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-347 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-348
Normal numbers of male and female gametocytes are produced. Male and female gamete formation is normal(escape from host red blood cell, formation of 8 motile male gametes). Female gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%). Motile males fail to attach to and penetrate female gametes.Mutant male gametes are fertile as shown by cross-fertilisation with wild type female gametes.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-347
Normal numbers of male and female gametocytes are produced. Male and female gamete formation is normal(escape from host red blood cell, formation of 8 motile male gametes). Female gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%). Motile males fail to attach to and penetrate female gametes.Mutant male gametes are fertile as shown by cross-fertilisation with wild type female gametes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-348
Female gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%). Motile males fail to attach to and penetrate female gametes.Mutant male gametes are fertile as shown by cross-fertilisation with wild type female gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-347
Female gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%). Motile males fail to attach to and penetrate female gametes.Mutant male gametes are fertile as shown by cross-fertilisation with wild type female gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-348 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-347 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-348 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-347 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-348 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-347 Imported from RMgmDB

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