Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-525 Imported from RMgmDB
P. falciparum 3D7
Refractory
22127061 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-525 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-525 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-525 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-525 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-525 Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-525
transmitted by mosquito bite
Imported from RMgmDB

Imaging data (from Malaria Metabolic Pathways)

Confocal immunofluorescence images, Left column (red): PfPK5 immunofluorescence; middle column (green): TOT0 1; right column: composite. (A) Parasites of various ages - upper row: two parasites, less than 30 h old; middle row: parasite, 30-36 h old; lower row: parasite, older than 40 h. The upper two size bars are 2.5 mm, the one in the bottom row 2 mm. (B) Three parasites at the time of nuclear divisions. Note the nuclear localization of PfPK5. The size bar is 5 mm.Graeser R, Wernli B, Franklin RM, Kappes B. Plasmodium falciparum protein kinase 5 and the malarial nuclear division cycles. Mol Biochem Parasitol. 1996 82:37-49. Copyright Elsevier 2009.

See original on MMP

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