Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-1100 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1100
Strongly reduced growth of asexual blood stages. Evidence is presented that parasites can only develop into mature schizonts in reticulocytes and not in normocytes
Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1100
Lower production of male and female gametocytes. Reduced exflagellation of male gametocytes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-1100
Lower production of male and female gametocytes. Reduced exflagellation of male gametocytes.Reduced ookinete production
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1100
Reduced ookinete productionReduced oocyst productionAberrant formation of oocysts: reduced size and absence of sporogony (sporozoite formation)
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1100
Reduced ookinete productionReduced oocyst productionAberrant formation of oocysts: reduced size and absence of sporogony (sporozoite formation)Absence of salivary gland sporozoites
Imported from RMgmDB

More information

PlasmoDB PKNH_1413300
GeneDB PKNH_1413300
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK13_1210w, PKH_141180
Orthologs PBANKA_1411100 , PCHAS_1413000 , PF3D7_1312600 , PVP01_1413600 , PVX_122460 , PY17X_1412900
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