Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-229 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4548 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4548 Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-229
Mutant parasites produced fewer salivary gland sporozoites (no quantitative data is provided on oocyst production and on the reduction in sporozoite formation). Sporozoites displayed enhanced migratory activity and were significantly less infective for hepatocytes
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-229
Sporozoites displayed enhanced migratory activity and were significantly less infective for hepatocytes. In vivo there was significant delay in the time to detectable blood-stage infection with mutant sporozoites compared to wild type.
Imported from RMgmDB

More information

PlasmoDB PKNH_0920600
GeneDB PKNH_0920600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK11_1990w, PKH_092030
Orthologs PBANKA_0925500 , PCHAS_0918900 , PF3D7_1122800 , PVP01_0923400 , PVX_091755 , PY17X_0927500
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