Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-363 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-363 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-363 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-363 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-363
Normal numbers of midgut ookinetes are produced. Ookinetes can invade and traverse the midgut epithelium comparable to wild type ookinetes. Ookinetes transform efficiently in oocysts but the number of oocysts declined as development proceeded. When analysed at day 15 after the infectious blood meal, neither mature oocysts nor sporozoites could be detected. In a few mosquitoes small, disintegrating oocysts were observed.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-363
No mature oocysts and (oocyst-derived) sporozoites are formed
Imported from RMgmDB

More information

PlasmoDB PKNH_0820800
GeneDB PKNH_0820800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK3_1750c, PKH_082060
Orthologs PBANKA_1218100 , PCHAS_1218800 , PF3D7_0320400 , PVP01_0819800 , PVX_095215 , PY17X_1221300
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