Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Cytolocalization of P. falciparum folate transporters PfFT1 and PfFT2. A, fluorescence signals given by P. falciparum transformed with a PfFT1-GFP C-terminal fusion construct are shown. A trophozoite (top panels) shows a signal that coincides with the parasites plasma membrane. Dividing stages of early and late schizonts are in the two lower panels. In the schizonts the labeling of merozoite plasma membranes is apparent. B, indirect immunofluorescence of PfFT2 is shown. Permeabilized cells were labeled with an anti-PfFT2 antibody. Again trophozoites (upper and middle panels) as well as merozoites in the schizont in the lower panel presented strong plasma membrane signal. Bars represent 2mm.Salcedo-Sora JE, Ochong E, Beveridge S, Johnson D, Nzila A, Biagini GA, Stocks PA, O'Neill PM, Krishna S, Bray PG, Ward SA. The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters. J Biol Chem. 2011286(52):44659-68.

See original on MMP

More information

PlasmoDB PKNH_0114700
GeneDB PKNH_0114700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PK8_0350w, PKH_011410
Orthologs PBANKA_1226100 , PCHAS_1226700 , PF3D7_0804500 , PVP01_0116000 , PVX_093535 , PY17X_1229300
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