Last updated 1 year ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
11163248
male-specific defect
Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-346 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-345 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-15 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4520 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Gametocyte
Difference from wild-type
11163248
male-specific defect
Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Asexual
No difference
RMgm-346 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-345 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-15 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4520 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-346
Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%); Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilization with wild type male gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-345
Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%); Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilization with wild type male gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-15
Normal numbers of male and female gametocytes are produced. Male and female gamete formation is normal(escape from host red blood cell, formation of 8 motile male gametes). Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%). Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilisation with wild type male gametes.
Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4520 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-346
Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%); Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilization with wild type male gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-345
Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%); Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilization with wild type male gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-15
Male gametes are strongly affected in their fertility, resulting in nearly complete inhibition of ookinete formation in vitro (>0.99%); Motile males fail to attach to and penetrate female gametes.Mutant female gametes are fertile as shown by cross-fertilization with wild type male gametes.Mutant parasites produce low numbers of ookinetes in vivo (Anopheles stephensi). See also 'Additional remarks phenotype'.
Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-346 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-345 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-15 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-346 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-345 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-15 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-346 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-345 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-15 Imported from RMgmDB

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