PF3D7_1344800 aspartate carbamoyltransferase (ATCase)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Refractory |
RMgm-1275 | Imported from RMgmDB | |
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Fluorescent microscopy imaging of P. falciparum transfected with GFP-labelled PfATC shows distinct localization of PfATC. GFP-labelling experiments in vivo showed distinct localization of PfATC compared with the ER, supporting the hypothesis of the apicomplexian nature of the enzyme.Lunev S, Bosch SS, Batista Fde A, Wrenger C, Groves MR. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallogr F Struct Biol Commun. 2016 72:523-33.
See original on MMPMore information
| PlasmoDB | PF3D7_1344800 |
| GeneDB | PF3D7_1344800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL13P1.221, PF13_0240 |
| Orthologs | PBANKA_1357700 , PCHAS_1362300 , PKNH_1256500 , PVP01_1210000 , PVX_083135 , PY17X_1363400 |
| Google Scholar | Search for all mentions of this gene |