Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-1049 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4873 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-1049 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4873 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-1049 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4873 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-1049 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4873 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1049
Normal oocyst size and numbers. No sporozoites formed 14 or 21 days post-infection
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4873
While the overall number of oocysts observed in deh and WT lines was not significantly different, there was a significant reduction in deh GFP-expressing oocysts beginning at day 7 and continuing through day 21 post-infection, with many appearing to be degenerating and were reduced in size compared to wild type oocysts. deh oocysts showed numerous cytoplasmic vacuoles with evidence of dilatation of the nuclear membranes.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1049
Normal oocyst size and numbers. No sporozoites formed 14 or 21 days post-infection
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4873
No salivary gland sporozoites
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1049
Not transmitted
Imported from RMgmDB

More information

PlasmoDB PF3D7_1331600
GeneDB PF3D7_1331600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL13P1.168
Orthologs PBANKA_1346500 , PCHAS_1351100 , PKNH_1268900 , PVP01_1223000 , PVX_082515 , PY17X_1351400
Google Scholar Search for all mentions of this gene