Last updated 2 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
https://www.biorxiv.org/content/10.1101/2020.06.18.160663v1.abstract
"We found that PfFis1 45 requires an intact C-terminus for mitochondrial localization but is not essential for parasite 46 development or mitochondrial fission. The dispensable role of PfFis1 indicates Plasmodium 47 contains additional fission adaptor proteins on the mitochondrial outer membrane that could be 48 essential for mitochondrial fission. "
Theo Sanderson, Francis Crick Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
No difference
https://www.biorxiv.org/content/10.1101/2020.06.18.160663v1.abstract
"We found that PfFis1 45 requires an intact C-terminus for mitochondrial localization but is not essential for parasite 46 development or mitochondrial fission. The dispensable role of PfFis1 indicates Plasmodium 47 contains additional fission adaptor proteins on the mitochondrial outer membrane that could be 48 essential for mitochondrial fission. "
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PF3D7_1325600
GeneDB PF3D7_1325600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL13P1.139
Orthologs PBANKA_1340700 , PCHAS_1345300 , PKNH_1203200 , PVP01_1229000 , PVX_116600 , PY17X_1345400
Google Scholar Search for all mentions of this gene