Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5033 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5072 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5073 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-5033 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5072 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5073 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5033
two independent disruptants were obtained. Mature-appearing female and male gametocytes were observed in Giemsa-stained blood smears. However, in ookinete culture, they failed to develop into mature ookinetes. In mosquito transmission experiments, no oocysts were found in the midgut 14 days after mosquito blood-feeding.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5072
Infertile females, males fertile (reduced male fertility?).
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-5073
Infertile females, males fertile (reduced male fertility?).
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5033
two independent disruptants were obtained. Mature-appearing female and male gametocytes were observed in Giemsa-stained blood smears. However, in ookinete culture, they failed to develop into mature ookinetes. In mosquito transmission experiments, no oocysts were found in the midgut 14 days after mosquito blood-feeding.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5072
Infertile females, males fertile (reduced male fertility?). Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5073
Infertile females, males fertile (reduced male fertility?).Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5033
Two independent disruptants were obtained. Mature-appearing female and male gametocytes were observed in Giemsa-stained blood smears. However, in ookinete culture, they failed to develop into mature ookinetes. In mosquito transmission experiments, no oocysts were found in the midgut 14 days after mosquito blood-feeding.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5072
Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5073
Complete (or nearly complete) loss in the ability to form oocysts in mosquitoes
Imported from RMgmDB

More information