Last updated 4 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
18614010 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Gametocyte
Attenuated
23572579 (Insert. mut.) Theo Sanderson, Wellcome Trust Sanger Institute

Imaging data (from Malaria Metabolic Pathways)

Localization of PfGECO (HSP40) to the host RBC during gametocytogenesis. IFA was performed on wild type 3D7 gametocyte stages I-V using anti-PfGECO serum (red) with the nucleus stained with DAPI (4,6-diamidino-2-phenylindole; blue). Also shown are the bright field (BF) and merged images.Morahan BJ, Strobel C, Hasan U, Czesny B, Mantel PY, Marti M, Eksi S, Williamson KC. Functional analysis of the exported type IV HSP40 protein PfGECO in P. falciparum gametocytes. Eukaryot Cell. 2011 10(11):1492-503.

See original on MMP

PfGECO is external to Pfs16 and internal to MESA. Co-localization IFA was performed on gametocyte stages I-IV using anti-PfGECO serum (red) and either (A) anti-Pfs16 (green) serum or (B) anti-MESA (green) serum. Also shown is the parasite nucleus stained with DAPI (blue), the bright field (BF) and the merged images.Morahan BJ, Strobel C, Hasan U, Czesny B, Mantel PY, Marti M, Eksi S, Williamson KC. Functional analysis of the exported type IV HSP40 protein PfGECO in P. falciparum gametocytes. Eukaryot Cell. 2011 10(11):1492-503.

See original on MMP

More information

PlasmoDB PF3D7_1253000
GeneDB PF3D7_1253000
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2277.t00508, PF12_0010, PFL2550w
Orthologs
Google Scholar Search for all mentions of this gene