Last updated 8 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
22127061 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
RMgm-564 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-247 Imported from RMgmDB
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Immunofluorescence analysis. Synchronized asexual parasites were stained with the immunopurified rabbit anti-Pfnek-1 antibody (top panels). The two bottom panels display negative controls using pre-immune serum. Scale bar: 5mm. Fluorescent dots are observed near the nuclei at the ring and schizont stages, whereas the pattern was more diffused and appeared as largely cytoplasmic in trophozoitesDorin-Semblat D, Schmitt S, Semblat JP, Sicard A, Reininger L, Goldring D, Patterson S, Quashie N, Chakrabarti D, Meijer L, Doerig C. Plasmodium falciparum NIMA-related kinase Pfnek-1: sex-specificity and assessment of essentiality for the erythrocytic asexual cycle. Microbiology. 2011 157(Pt 10):2785-94 Copyright Society for General Microbiology 2011.

See original on MMP

More information

PlasmoDB PF3D7_1228300
GeneDB PF3D7_1228300
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2277.t00274, MAL12P1.274, PFL1370w
Orthologs PBANKA_1443000 , PCHAS_1445200 , PKNH_1447700 , PVP01_1446500 , PVX_124045 , PY17X_1445500
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