Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-312 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-312 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-312 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-312 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-312
Normal numbers of oocysts are produced. In mature oocysts sporozoites are formed comparable to wild type. However, sporozoites do not egress from the oocysts (and only very low numbers of hemocoel sporozoites are detected)
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-312
Sporozoites do not egress from the oocysts. Only very low numbers of hemocoel sporozoites are detected. Analysis of dissected salivary glands showed very low numbers of sporozoites (3800 sporozoites) compared to wild type (126.500 sporozoites). No further analysis was performed to determine whether these sporozoites are inside the salivary glands or were attached to the outside of the glands.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-312
No blood stage infection after infection of mice by bite of infected mosquitoes
Imported from RMgmDB

More information

PlasmoDB PF3D7_1218100
GeneDB PF3D7_1218100
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2277.t00175, MAL12P1.175, PFL0875w
Orthologs PBANKA_1433700 , PCHAS_1435700 , PKNH_1437700 , PVP01_1436900 , PVX_123580 , PY17X_1436100
Google Scholar Search for all mentions of this gene