Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Localisation of PFL0625c during the IDC. Localisation of the tagged protein was visualised using anti-Ty antibodies (red). Antibodies against PfBIP were used to visualise the ER. DAPI was used to visualise the nucleus. DIC images are shown as reference. The bromodomain protein with a more restricted and peripheral localization in ring stages and a diffuse nuclear pattern in trophozoites and schizonts.Oehring SC, Woodcroft BJ, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Maeser P, Flueck C, Witmer K, Brancucci NM, Niederwieser I, Jenoe P, Ralph SA, Voss TS. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol. 2012 Nov 26;13(11):R108.

See original on MMP

Localisation of PFL0625c during the IDC. Localisation of the tagged protein was visualised using anti-Ty antibodies (red). Antibodies against PfBIP were used to visualise the ER. DAPI was used to visualise the nucleus. DIC images are shown as reference. The bromodomain protein with a more restricted and peripheral localization in ring stages and a diffuse nuclear pattern in trophozoites and schizonts.Oehring SC, Woodcroft BJ, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Maeser P, Flueck C, Witmer K, Brancucci NM, Niederwieser I, Jenoe P, Ralph SA, Voss TS. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol. 2012 Nov 26;13(11):R108.

See original on MMP

More information

PlasmoDB PF3D7_1212900
GeneDB PF3D7_1212900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2277.t00128, MAL12P1.127, PFL0635c
Orthologs PBANKA_1428900 , PCHAS_1430700 , PKNH_1432300 , PVP01_1431800 , PVX_123350 , PY17X_1431000
Google Scholar Search for all mentions of this gene