PF3D7_1200800 serine/threonine protein kinase, FIKK family (FIKK12)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Possible |
20668526 | Theo Sanderson, Wellcome Trust Sanger Institute |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
No difference |
20668526 | Theo Sanderson, Wellcome Trust Sanger Institute |
Imaging data (from Malaria Metabolic Pathways)
Upper panel: Immuno-localization of the FIKK12-GFP chimera in transgenic parasites. First image GFP fluorescence, second image cells incubated with anti-FIKK12 antibody, third image overlay of first and second image showing that FIKK12-GFP colocalizes with anti-FIKK12 at the surface of the infected RBC.Lower panel: Colocalization of FIKK12 with PfSBP1 in ring stage P. falciparum-infected erythrocytes. Second row: colocalization is lost at the trophozoite stage.Nunes MC, Goldring JP, Doerig C, Scherf A. A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell. Mol Microbiol. 2007 63:391-403.
See original on MMPMore information
| PlasmoDB | PF3D7_1200800 |
| GeneDB | PF3D7_1200800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | 2277.t00008, MAL12P1.8, PFL0040c |
| Orthologs | |
| Google Scholar | Search for all mentions of this gene |