PF3D7_1117600 peptidyl-tRNA hydrolase ICT1, peptidyl-tRNA hydrolase ICT1, putative (ICT1)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
Molecular modeling, detection and subcellular localization of PfICT1. (D-F) Immunofluorescence assay for localization of PfICT1 using purified anti-PfICT1 Ab. Overlap of the PfICT1 signal was seen with the mitochondrial dye (D) and 3-dimensional reconstruction after z-sectioning showed clear overlay of PfICT1 signal with the mitochondrion (E). No overlap was observed with the apicoplast marker PfHU (F).Vaishya S, Kumar V, Gupta A, Siddiqi MI, Habib S. Polypeptide release factors and stop codon recognition in the apicoplast and mitochondrion of Plasmodium falciparum. Mol Microbiol. 2016 Mar 4. [Epub ahead of print] PMID:
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| PlasmoDB | PF3D7_1117600 |
| GeneDB | PF3D7_1117600 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF11_0182, PF3D7_1117600.1, PF3D7_1117600.2 |
| Orthologs | PBANKA_0930400 , PCHAS_0913900 , PKNH_0915300 , PVP01_0918200 , PVX_091510 , PY17X_0932400 |
| Google Scholar | Search for all mentions of this gene |