Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5231 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-5231 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5231 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-5231 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5231
A significant decrease (approx. 70%) in the number of oocysts at day 9 post-infection and oocysts at this stage of development were smaller in size.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5231
Despite the overall smaller oocyst numbers and sizes in the PbLRR1KO lines, a substantial proportion of oocysts completed development to sporozoites and no significant effects on salivary gland colonization were observed. Sporozoites were infective in both in vitro hepatocyte cultures and in mice, albeit with a slightly longer prepatent period.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-5231
Sporozoites were infective in both in vitro hepatocyte cultures and in mice, albeit with a slightly longer prepatent period.
Imported from RMgmDB

More information

PlasmoDB PF3D7_1032800
GeneDB PF3D7_1032800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PF10_0320, PF10_0320a
Orthologs PBANKA_0516600 , PCHAS_0516700 , PKNH_0617600 , PVP01_0617900 , PVX_111085 , PY17X_0517700
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