Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-4652 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4652
Slightly reduced growth rate of asexual blood stages (no ECM pathology in C57Bl6 mice; mice die from hyperparasitemia. BALB/c developed hyperparasitemia but were able to clear infection)
Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4652 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4652
no oocyst formation
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4652
No oocyst formation; no sporozoite formation
Imported from RMgmDB

More information