Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Expression and localization of Kae1api interaction partners. Representative IFA images from RFA-tagged parasites are shown. IspG (top row), EF-Ts (middle row), and a putative RNA helicase (bottom row) co-localize with an apicoplast marker (ACP) and not with mitochondria. Mitochondria and nuclei were visualized with Mitotracker and DAPI-DNA stain, respectively. IFAstudies confirmed the apicoplast localization of all three proteins.Mallari JP, Oksman A, Vaupel B, Goldberg DE. Kinase-Associated Endopeptidase 1 (Kae1) Participates in an Atypical ribosome-Aassociated complex in the apicoplast of Plasmodium falciparum. J Biol Chem. 2014 Sep 9 [Epub ahead of print]

See original on MMP

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