Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-4956 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4956 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4956
Reduced production of gametocytes, reduced exflagellation of male gametocytes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4956
Reduced numbers of oocysts. Oocysts remain small and no sporozoite formation inside oocysts. While up until day 4 the oocyst size was comparable between mutant and wild type oocysts, over time uis12(-) oocysts displayed an abnormal morphology. Their size remained unchanged, whereas the wild type oocyst diameter increased ~10-fold over the following ten days.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4956
No midgut or salivary gland sporozoites
Imported from RMgmDB

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