P. falciparum in vitro blood stages labeled with antibodies recognizing PF10_0164. Parasites were from synchronized cultures, fixed at the indicated developmental stage. The protein appears to be absent in rings. It localizes to the PV in trophozoites and gametocytes, and is exported to the hosterythrocyte in schizonts and some trophozoites. Overlay images in all figures include DAPI for labeling nuclei. Scale bar = 5 micrometers.Mackellar DC, O'Neill MT, Aly AS, Sacci JB Jr, Cowman AF, Kappe SH. Plasmodium falciparum PF10_0164 (ETRAMP10.3) is an essential parasitophorous vacuole and exported protein of blood stages. Eukaryot Cell. 2010 9:784-94.

Effect of Torin2 treatment on the PVM and UIS4 localization in young liver stage trophozoites. (C) Effect of Torin2 treatment on UIS4 and EXP1 during early liver stage schizogony. UIS4 and EXP1 were localized almost completely outside of the parasite soma in control. Torin2 treatment led to a dramatic mislocalization of UIS4 and EXP1, with signal largely found in the parasite soma.Hanson KK, Ressurreição AS, Buchholz K, Prudêncio M, Herman-Ornelas JD, Rebelo M, Beatty WL, Wirth DF, Hänscheid T, Moreira R, Marti M, Mota MM. Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A. 2013 110(30):E2838-47.