PF3D7_1012400 hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
Sections of mature merozoites probed with anti-PfHRT serum and visualized for electron microscopy with gold-labeled secondary antibodies. By IFA PfHRT seems to be localized in vesicle-like structures in the host RBC cytosol.Shahabuddin M, Günther K, Lingelbach K, Aikawa M, Schreiber M, Ridley RG, Scaife JG. Localisation of hypoxanthine phosphoribosyl transferase in the malaria parasite Plasmodium falciparum. Exp Parasitol. 1992 74:11-9. Copyright Elsevier 2010.
See original on MMPMore information
| PlasmoDB | PF3D7_1012400 |
| GeneDB | PF3D7_1012400 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF10_0121 |
| Orthologs | PBANKA_1210800 , PCHAS_1211500 , PKNH_0812200 , PVP01_0812500 , PVX_094840 |
| Google Scholar | Search for all mentions of this gene |