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Disruptability [+]

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Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
https://www.biorxiv.org/content/10.1101/2020.06.02.130229v1 (Conditional)
Using a conditional knockdown strain, we show that Pf3D7_0913500 depletion causes growth inhibition that is rescued by the sole essential product of the apicoplast, isopentenyl pyrophosphate (IPP), and results in apicoplast loss.
Theo Sanderson, Francis Crick Institute

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