Last updated 8 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
31650539 Theo Sanderson, Francis Crick Institute

Mutant phenotypes [+]

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Imaging data (from Malaria Metabolic Pathways)

Localization by immunofluorescence of FIKK4.1, FIKK9.2, FIKK9.3 and FIKK9.6 proteins in 3D7 parasites. A and B. Ring stage (A) and trophozoite stage (B) P. falciparum-infected erythrocytes were air dried and immunolabelled with PfSBP1 antibody (red) and a FIKK-specific antibody (green). First row: polyclonal guinea pig anti-FIKK4.1; second row: polyclonal guinea pig anti-FIKK9.3; third row: polyclonal rat anti-FIKK9.6; last row: chicken anti-FIKK9.2. The third column in each panel represents the merging of the red and green channels. Yellow areas represent regions of colocalization seen on both parasitic stages for all the FIKK proteins except FIKK9.2. All proteins (not FIKK9.2) localize to the Maurer’s clefts.Nunes MC, Goldring JP, Doerig C, Scherf A. A novel protein kinase family in Plasmodium falciparum is differentially transcribed and secreted to various cellular compartments of the host cell. Mol Microbiol. 2007 63:391-403.

See original on MMP

More information

PlasmoDB PF3D7_0902500
GeneDB PF3D7_0902500
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PFI0120c
Google Scholar Search for all mentions of this gene