| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
Attenuated |
36306288 (Knock down)
\"Genetic ablation of PfHtrA2 caused significant parasite growth inhibition, decreased replication of mtDNA, increased mitochondrial ROS production, caused mitochondrial fission/fragmentation, and hindered parasite development. However, the ucf-101 treatment did not affect the parasite growth, suggesting the non-protease/chaperone role of PfHtrA2 in the parasite. \" |
Theo Sanderson, Francis Crick Institute |
| PlasmoDB | PF3D7_0812200 |
| GeneDB | PF3D7_0812200 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL8P1.98, MAL8P1.99 |
| Orthologs | PBANKA_1425300 , PBANKA_1425350 , PCHAS_1427100 , PCHAS_1427150 , PKNH_1428400 , PKNH_1428500 , PVP01_1428000 , PVP01_1428100 , PVX_123158 , PVX_123162 , PY17X_1427300 , PY17X_1427400 |
| Google Scholar | Search for all mentions of this gene |