Last updated 3 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
20466936 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-4155 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-12 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4155 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
No difference
20466936 (Conditional) Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Asexual
No difference
RMgm-4155 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-12 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4155 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes.
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-12
No male gametes are formed; Male gametocytes are not affected in the ability to 'round up'and lyse the host cell; in male gametocytes axoneme formation, formation of mitotic spindles and DNA synthesis is inhibited/blocked.Female gametes are fertile; mutant female gametes fertilised by wild type male gametes produce ookinetes. However, these ookinetes are strongly affected in their ability to produce oocysts
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes (no exflagellation).
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-12
See the description of the phenotype of Gametocytes/Gametes and Additional remarks phenotype
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4155
No male gametes are formed after activation of male gametocytes (no exflagellation).
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-12
See the description of the phenotype of Gametocytes/Gametes and 'Additional remarks phenotype'.
Imported from RMgmDB

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