Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

GFP targeting by various P. falciparum redox proteins of the glutathione system. (A) Cytosolic localization of GLP1. (B) Cytosolic localization of GLP2. (C) Dual localization (cytosol and apicoplast) of the tGloII N-terminus. (D) PV-localization of the signal peptide of GR (the parasites showed a fast bleaching fluorescence, leading to a high background signal). Live cell imaging of erythrocytes infected with transgenic parasites for solely cytosolic GFP signals. Colocalization of GFP and the apicoplast marker ACP in fixed, immunodecorated cells.Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 6:e1001242.

See original on MMP

More information

PlasmoDB PF3D7_0606900
GeneDB PF3D7_0606900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 2270.t00247, MAL6P1.72, PFF0340c
Orthologs PBANKA_0105500 , PCHAS_0106100 , PKNH_1143400 , PVP01_1142100 , PVX_113510 , PY17X_0107000
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