Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Confocal fluorescent images in panels A, C, and E show intense labeling of the erythrocyte plasma membrane (A, ring stage), the parasite (C, trophozoite stage), or both parasites and erythrocyte cytosol (bright dots) and the plasma membrane of the erythrocytes (E, trophozoite stage) as detected using antibody against the B subunit of P. falciparum V-H+-ATPase (red). Panel G shows the lack of labeling of uninfected erythrocytes by epifluorescence microscopy. Panels B, D, F, and H show the bright field pictures of the same cells. Arrows in H show infected erythrocytes. Bars (for A–G) = 2.0 mm. Parasite-encoded vacuolar (V)-H+-ATPase is exported to the erythrocyte and localized in membranous structures and in the plasma membrane of the infected erythrocyte.Marchesini N, Vieira M, Luo S, Moreno SN, Docampo R. A malaria parasite-encoded vacuolar H+-ATPase is targeted to the host erythrocyte. J Biol Chem. 2005 280:36841-7.

See original on MMP

More information

PlasmoDB PF3D7_0406100
GeneDB PF3D7_0406100
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL4P1.60, PFD0300c, PFD0305c
Orthologs PBANKA_1003800 , PCHAS_1004700 , PKNH_0304200 , PVP01_0305500 , PVX_000935 , PY17X_1005200
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