Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Expression of PfRNF1 in blood stage parasites using the PfRNF1-HA-Strep parasite line. Anti-HA were used to immunolabel fixed samples of trophozoites, schizonts and mature gametocytes (GC) as well as of activated gametocytes (aGC) at 30 min post-activation (green). Schizonts were visualized by labelling with mouse anti-proteasome α5 and gametocytes were visualized by mouse anti-Pfs230 (red); nuclei were highlighted by Hoechst nuclear stain 33342 (blue). Bar, 5 µm. Weißbach T, Golzmann A, Bennink S, Pradel G, Julius Ngwa C. Transcript and protein expression analysis of proteases in the blood stages of Plasmodium falciparum. Exp Parasitol. 2017 Mar 25. [Epub ahead of print]

See original on MMP

More information

PlasmoDB PF3D7_0314700
GeneDB PF3D7_0314700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL3P5.8, PFC0610c
Orthologs PBANKA_0412400 , PCHAS_0413300 , PKNH_0827400 , PVP01_0825400 , PVX_119830 , PY17X_0415300
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