Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
RMgm-1055 Imported from RMgmDB

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Expression and localization of PfPTPA-GFP (d) and PfPP2A-GFP (e) throughout the erythrocytic cell cycle of P. falciparum were analyzed by fluorescence microscopy after transfection. Examination of live parasites transfected with pfptpa-gfp showed that the signal was confined within the parasite where the distribution is nucleo-cytoplasmic in rings, trophozoites and schizonts (d), as the fluorescence partially overlapped DNA staining. Parasites transfected with the construct containing pfpp2a-gfp showed a nucleo-cytoplasmic distribution in rings and schizonts with an intense accumulation in the nucleus of late trophozoites.Vandomme A, Fréville A, Cailliau K, Kalamou H, Bodart JF, Khalife J, Pierrot C. PhosphoTyrosyl Phosphatase Activator of Plasmodium falciparum: Identification of Its Residues Involved in Binding to and Activation of PP2A. Int J Mol Sci. 2014 15(2):2431-53.

See original on MMP

More information

PlasmoDB PF3D7_0314400
GeneDB PF3D7_0314400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL3P5.5, PFC0595c
Orthologs PBANKA_0412100 , PCHAS_0413000 , PKNH_0827700 , PVP01_0825700 , PVX_119815 , PY17X_0415000
Google Scholar Search for all mentions of this gene