Last updated 9 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
30581113 (Conditional)
\"Here, we identify P. falciparum VPS45 as an essential factor in HCCU. Conditional inactivation of PfVPS45 led to an accumulation of host cell cytosol-filled vesicles within the parasite and inhibited the delivery of hemoglobin to the parasite\'s digestive vacuole, resulting in arrested parasite growth. \"
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PF3D7_0216400
GeneDB PF3D7_0216400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PF02_0154, PFB0750w
Orthologs PBANKA_0313100 , PCHAS_0315200 , PKNH_0404500 , PVP01_0408600 , PVX_002720 , PY17X_0313600
Google Scholar Search for all mentions of this gene