Last updated 4 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
RMgm-540 Imported from RMgmDB
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4677 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4677 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4677 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4677 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-4677 Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4677
Normal sporozoite production. Pbstk2 KO sporozoites exhibit normal gliding motility, cell traversal activity, and infection of hepatocytes in vitro.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-4677
Normal sporozoite production. Pbstk2 KO sporozoites exhibit normal gliding motility, cell traversal activity, and infection of hepatocytes in vitro. Prolonged prepatent period after infection of mice by intravenous injection of sporozoites. Evidence is presented for reduced hepatic schizogony and merozoite maturation (reduced MSP1 expression).
Imported from RMgmDB

More information

PlasmoDB PF3D7_0214600
GeneDB PF3D7_0214600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PF02_0137, PFB0665w
Orthologs PBANKA_0311400 , PCHAS_0313500 , PKNH_0406200 , PVP01_0410300 , PVX_002805 , PY17X_0311900
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