Last updated 3 months ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Refractory
35277503 (Knock down)
\'In this study, we use inducible knockdown studies in the human malaria parasite, Plasmodium falciparum, to show that two RAP proteins, PF3D7_0105200 (PfRAP01) and PF3D7_1470600 (PfRAP21), are essential for parasite survival and localize to the mitochondrion. Using transcriptomics, metabolomics, and proteomics profiling experiments, we further demonstrate that these RAP proteins are involved in mitochondrial RNA metabolism. \'
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PF3D7_0105200
GeneDB PF3D7_0105200
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) MAL1P1.42, PFA0255c
Orthologs PBANKA_0208100 , PCHAS_0206500 , PKNH_0208500 , PVP01_0209600 , PVX_081505 , PY17X_0209500
Google Scholar Search for all mentions of this gene