Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4855 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-4855 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4855 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4855
Normal numbers of gametocytes are produced. Whereas, pbqsox deletion did not affect the formation of macrogametes, it reduced the number of exflagellation centers by 28.0%. Ookinetes in the pbqsox line retained normal morphology, but the proportion of mature ookinetes (stage IV-VI) was reduced by 43.1%.Consistent with the in vitro ookinete conversion result, the number of ookinetes formed in the blood bolus of mosquitoes feeding on pbqsox-infected mice was 60.264.6% lower than that with the WT parasites.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4855
A 61.862.8% reduction in oocyst number/midgut in mosquitoes after feeding on pbqsox-infected mice as compared to those fed on WT parasite-infected mice. The gross morphology of oocysts appeared normal in the pbqsox parasites compared to the WT
Imported from RMgmDB

More information

PlasmoDB PCHAS_1457700
GeneDB PCHAS_1457700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000280.02.0, PCAS_145770, PCHAS_145770
Orthologs PBANKA_1455400 , PF3D7_1242000 , PKNH_1461300 , PVP01_1459100 , PVX_101000 , PY17X_1457900
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