Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-1411 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Possible
RMgm-4786 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1411
Reduced growth/multiplication of asexual blood stages.Parasitemias in Pbvit- infected mice were significantly reduced, when compared with those in mice infected with wild-type (wt) parasites. Furthermore, C57Bl/6 J mice infected with Pbvit- parasites (104 infected RBC i.v.) survived significantly longer compared with mice infected with wt parasites.
Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. yoelii yoelii 17X Asexual
No difference
RMgm-4786 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-1411 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4786
normal production of gametocytes; normal exflagellation
Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-1411 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-1411 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-1411 Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1411
Reduced liver stage development.A significant reduction in parasite liver load was detected after Pbvit- sporozoite infection. The observed reduction in parasite liver load was due to a lower number of infected hepatocytes, as well as moderate reduction in size of developing Pbvit- exoerythrocytic parasite formsEEFs.
Imported from RMgmDB

More information

PlasmoDB PCHAS_1440600
GeneDB PCHAS_1440600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000337.03.0, PC300212.00.0, PCAS_144060, PCHAS_144060
Orthologs PBANKA_1438600 , PF3D7_1223700 , PKNH_1442900 , PVP01_1441900 , PVX_123815 , PY17X_1441100
Google Scholar Search for all mentions of this gene