Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
RMgm-4481 Imported from RMgmDB
P. falciparum 3D7
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
Parasites lacking PbmaLS_05 showed a decreased ability to infect RBC (and immature reticulocytes), resulting in reduced peripheral parasite loads. Reduced mortality due to experimental cerebral malaria (ECM). None of the mice infected with mutant sporozoites developed ECM; in contrast, mice infected with WT sporozoites, displayed signs of ECM between day 7 and 9 p.i. Mice die from high parasitemia and anemia.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
No data provided. Assuming normal sporozoite production.
Imported from RMgmDB

More information

PlasmoDB PCHAS_1402900
GeneDB PCHAS_1402900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000194.05.0, PC301032.00.0, PC301537.00.0, PC301719.00.0, PC302642.00.0, PCAS_140290, PCHAS_140290
Orthologs PBANKA_1401000 , PF3D7_1302500 , PKNH_1402700 , PVP01_1403400 , PVX_121965 , PY17X_1402600
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