Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5056 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5057 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-5058 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-5056 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5057 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-5058 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5056 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5057 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5058 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-5056 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-5057 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-5058 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5056
Normal numbers of oocysts are produced. On day 10 after infection melanized oocysts are present in 55-65% of QC-null infected mosquitoes (1-85 melanized oocysts/mosquito), while such oocysts were absent in WT-infected mosquitoes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5057
Normal numbers of oocysts are produced. On day 10 after infection melanized oocysts are present in 55-65% of QC-null infected mosquitoes (1-85 melanized oocysts/mosquito), while such oocysts were absent in WT-infected mosquitoes
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5058
Normal numbers of oocysts are produced. On day 10 after infection melanized oocysts are present in 55-65% of QC-null infected mosquitoes (1-85 melanized oocysts/mosquito), while such oocysts were absent in WT-infected mosquitoes
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5056
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Light-microscopy analysis of oocysts between day 14 and 21 showed the presence of aberrant, enlarged, melanized sporozoites, either still inside or during release from oocysts.On day 21 p.i. non-motile, enlarged sporozoites covered by melanin were found in the hemocoel, often in clusters or attached to salivary glands. In contrast, most QC-null sporozoites inside salivary glands had a WT-like morphology, i.e. long and slender, without signs of melanization.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5057
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Light-microscopy analysis of oocysts between day 14 and 21 showed the presence of aberrant, enlarged, melanized sporozoites, either still inside or during release from oocysts.On day 21 p.i. non-motile, enlarged sporozoites covered by melanin were found in the hemocoel, often in clusters or attached to salivary glands. In contrast, most QC-null sporozoites inside salivary glands had a WT-like morphology, i.e. long and slender, without signs of melanization.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-5058
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Light-microscopy analysis of oocysts between day 14 and 21 showed the presence of aberrant, enlarged, melanized sporozoites, either still inside or during release from oocysts.On day 21 p.i. non-motile, enlarged sporozoites covered by melanin were found in the hemocoel, often in clusters or attached to salivary glands. In contrast, most QC-null sporozoites inside salivary glands had a WT-like morphology, i.e. long and slender, without signs of melanization.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-5056
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Wild type development of liver stages in vitro.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-5057
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Wild type development of liver stages in vitro.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-5058
Reduced numbers of salivary gland sporozoites. Salivary gland sporozoites show wild-type morphology, motility and infectivity to hepatocytes in vitro. Wild type development of liver stages in vitro.
Imported from RMgmDB

More information

PlasmoDB PCHAS_1314000
GeneDB PCHAS_1314000
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000109.02.0, PCAS_131400, PCHAS_131400
Orthologs PBANKA_1310700 , PF3D7_1446900 , PKNH_1235300 , PVP01_1260100 , PVX_118150 , PY17X_1314500
Google Scholar Search for all mentions of this gene