Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
Refractory
34031901
\" In the work described here, we localized an enzyme responsible for coenzyme A synthesis, DPCK, to the apicoplast, but we were unable to delete DPCK, even in the presence of IPP. However, once the endogenous DPCK was complemented with the E. coli DPCK (EcDPCK), we were successful in deleting it. We were then able to show that DPCK activity is required for parasite survival through knockdown of the complemented EcDPCK. \"
Theo Sanderson, Francis Crick Institute
P. yoelii yoelii 17X
Refractory
RMgm-4185 Imported from RMgmDB

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

More information

PlasmoDB PCHAS_1310800
GeneDB PCHAS_1310800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000628.00.0, PCAS_131080, PCHAS_131080
Orthologs PBANKA_1307600 , PF3D7_1443700 , PKNH_1238600 , PVP01_1263300 , PVX_118305 , PY17X_1311400
Google Scholar Search for all mentions of this gene