Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

GFP targeting by various P. falciparum redox proteins. (A) Apicoplast targeting of the AOP N-terminus. (B) Dual localization (cytosol and apicoplast) of the TPxGl N-terminal amino acid sequence. (C) ER-targeting of Trx3. (D) Mitochondrial targeting of Tlp2. (E) Mitochondrial targeting of GLP3. (F) Apicoplast targeting of the GILP N-terminal sequence. Colocalization of GFP with the mitochondrial dye MitoTrackerOrange in fixed cells. Colocalization of GFP and the apicoplast marker ACP PFB0385w or the ER marker BiP PF11_0098 in fixed, immunodecorated cells. Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 6:e1001242.

See original on MMP

More information

PlasmoDB PCHAS_1220400
GeneDB PCHAS_1220400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000540.02.0, PCAS_122040, PCHAS_122040
Orthologs PBANKA_1219700 , PF3D7_0709200 , PKNH_0107800 , PVP01_0109500 , PVX_087990 , PY17X_1222900
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